What is Profhilo® and why Everyone’s Talking About it

Discover the rejuvenating power of Profhilo® for glowing, hydrated skin across the Face, Neck, Décolletage, and Hand Rejuvenation and body.

A Fresh Approach to Natural Radiance

If you’ve ever looked in the mirror and thought - I don’t want to look different… I just want to look better -  then Profhilo® was made for you. It’s not about a new face or dramatic instant change – this product helps with softer skin where people say you look well, and not - What have you had done! This product is often referred to as  – injectable skincare!

Profhilo® is definitely growing in popularity at Refind Aesthetics. Highbury and Canonbury clients love it because it works on skin quality, not facial shape - it can ease crepiness, improves elasticity, and boosts luminosity across the face and those tricky areas to treat - neck, décolletage, and hands. The change is gradual  -  but you look like yourself but more refreshed.

The Evolution of Skin Rejuvenation

The modern aesthetic goal isn’t about erasing every line — it’s more about that natural radiance, balance and skin qulaity that looks healthy at any age. Environmental stress, hormonal changes, and time all deplete the skin’s natural hydration. As a result, your fine lines begin deepening, skin tone dulls, and elasticity fades. Unlike other dermal fillers, Profhilo® doesn’t mask these signs by adding volume and plumpness – instead it helps your skin quality and appearance through deep hydration and collagen stimulation.

Understanding the Role of Hydration in Youthful Skin

I feel I am always going on about hyaluronic acid (HA) but it is so important for skin hydration and hydration is the foundation of beautiful, glowing skin. HA is a naturally occurring substance and in the skin it binds to water molecules – this keeps your skin supple. Bad news – as we age, HA levels drop which makes your skin drier, thinner, and more prone to crepiness.

Profhilo® is a highly concentrated form of HA and it is more effective than traditional moisturisers which sit on the surface of your skin. By injecting skin with Profhilo®, the HA can  rehydrate the skin’s deeper layers – making more of an impact on your skin quality.

Profhilo® is also able to encourage production of collagen and elastin  – the scaffolding of your skin. So, in addition to effective hydration, it can help the skin regain firmness and elasticity – all without adding volume.

Because of its unique properties Profhilo® is frequently referred to as a bio-remodelling treatment for skin rejuvenation.

What Is Profhilo® and How Does It Work?

Profhilo® contains a pure, stabilised form of hyaluronic acid with two molecular weights. One of the molecules deeply hydrates and the other stimulates collagen and elastin production.

When injected, Profhilo®  spreads smoothly beneath the skin like honey. Over the following weeks, it encourages the skin to remodel itself — improving tone, elasticity, and overall radiance.

It is a great treatment for amazing looking skin – but make sure you factor in the time for peak effectiveness particularly if you have a big event coming up. It takes time to make a difference, and the effect is better with multiple treatments.

How Profhilo® Differs from Fillers and Skin Boosters

Unlike dermal fillers, Profhilo® doesn’t create volume or contour – this product acts like a skin conditioner, improving the skin’s texture and firmness. It’s the perfect option for anyone who wants fresher, tighter, more hydrated skin — without altering facial shape.

Profhilo® can also be a great complement other treatments like microneedling or skin boosters including polynucleotides, enhancing their effects for a comprehensive rejuvenation plan.

To find out more about Refind Aesthetics treatments using microneedling or skin boosters – read our blogs:

What are Exosomes and How do they support skin renewal?

Polynucleotides for rejuvanation from within – Why they’re growing in popularity.

Safety and Medical Expertise

Profhilo® is a medical treatment that should only be administered by trained healthcare professionals. At Refind Aesthetics, treatments are carried out by Dr. Dana Sobhanpanah, a GMC-registered doctor trained at Harley Academy. We use only genuine, CE-marked Profhilo® to ensure your safety and  consistency in the quality of the results.

Where does Profhilo® Works Best?

Can I use Profhilo® for Face Rejuvenation?

Profhilo® is ideal for restoring skin tone, elasticity, and hydration to the face. It smooths fine lines and softens creases without any impact on natural movement and expression. It’s also a wonderful complement to wrinkle-relaxing injections, providing hydration where muscle treatments focus on relaxation. If you want more information on wrinkle-relaxing injections read our blog: Is Botox® Right for Me? A Guide to Wrinkle-softening.

Can I use Profhilo® for Neck Rejuvenation?

Yes most definitely and excellent option for this area. It’s a sad fact that the neck often shows signs of ageing much earlier than the face – and it is much harder to treat. Options are limited but Profhilo® helps address fine lines, crepiness, and mild sagging. It can achieve this through strengthening the skin’s underlying structure – the collagen and elastin – which means you get a firmer, smoother contour.

Can I use Profhilo® for Décolletage Rejuvenation?

This is another area that ages badly and difficult to treat.  The Décolletage - the delicate skin of the chest area -  is very exposed to sun and environmental stress, which means as you age you see uneven tone and texture appearing. Profhilo® can treat this area without changing volume – you certainly don’t want that. Here Profhilo® deeply hydrates and smooths,  restoring  texture so it can appear more youthful.

Can I use Profhilo® on my hands?

As you know, even if you rejuvenate your face, your hands often reveal your age and can look out of sync with your newly refreshed features looks. Profhilo® can help – it can restore lost elasticity and hydration, softening the appearance of veins and tendons for smoother, plumper-looking skin. It is certainly a product worth trying if this is an area of concern.

Can I use Profhilo® for other areas of the Body?

Good news, the impact of Profhilo® isn’t limited to the face. It can be used on the upper arms, knees, and abdomen — anywhere skin texture has become lax or uneven. As body treatments become more refined, Profhilo® is leading the way in all-over skin rejuvenation.

The Profhilo® Experience at Refind Aesthetics

Every treatment begins with a face-to-face consultation – this is where we  assess your skin condition, review your medical history, and determine whether Profhilo® is suitable for you. This ensures your plan is bespoke, targeted, and medically sound – after all, your safety and requirements are our priority.

If Profhilo® is considered a suitable option, either on its own or as part of a treatment package -  the product is strategically injected at specific bio-aesthetic points designed for maximum coverage and minimal discomfort. The procedure takes around 30 minutes and requires no anaesthetic, although a light numbing cream can be used if preferred.

With this treatment, there’s little to no downtime. Mild redness or tenderness can occur but fades quickly. However, over the next few days, your skin begins its hydration phase. You may notice that your skin is looking plumper, smoother, and more luminous. The transformation continues gradually over 4–6 weeks as collagen and elastin renewal take hold.

When You’ll Notice the Profhilo® Glow

Most people start to notice improved texture and hydration within 10–14 days – so if you have an event coming up and want to look your best – make sure you have factored this into your plan. The process is best as part of a series of treatments – we usually recommend at least two treatment sessions spaced out for maximum results. By the end of the initial two-session treatment plan, skin appears smoother, tighter, and noticeably brighter.

How Long does Profhilo® last?

As with other non-surgical aesthetics treatments, results are not permanent  - your body will break down the HA over time. For Profhilo ® the results typically last up to six months. It all depends on age, skin quality, and lifestyle. To keep looking your best, it is a good idea to have maintenance treatments once or twice a year – this helps sustain hydration and collagen stimulation.

Can I Combine Profhilo® with Other Treatments?

Yes indeed, and this is probably an excellent strategy for most clients.

At Refind Aesthetics, we are all about a holistic care and Profhilo® integrates seamlessly into combination treatment plans.  For example, many of our clients from N1 use it to  enhance the results of microneedling, exosomes, polynucleotides and other injectables including dermal fillers and Botox ®. This combination approach offers a multi-dimensional approach to rejuvenation. Usually, we think about improving skin quality first, and then enhancing the outcome with other aesthetic treatments such as fillers or wrinkle-relaxing injections

Safety First: Why Practitioner Experience Matters

While Profhilo® is a safe, well-researched treatment, its success depends on the skill of the practitioner. It requires precise injection points, sterile technique, and anatomical knowledge to achieve safety, beautiful results.

Sadly, the UK’s lack of regulation means many unqualified injectors offer treatments using unverified products. At Refind Aesthetics, every treatment is performed by a GMC-registered doctor, using only genuine Profhilo® and medical-grade equipment.

Our philosophy is rooted in science, safety, and subtlety. Every treatment is led by Dr. Dana Sobhanpanah, whose background in medicine and aesthetic training ensures a holistic, medically informed approach. We believe true beauty lies in refinement, not reinvention.

Why Everyone’s Talking About Profhilo®?

This scientifically developed product, Profhilo®, is typical of the modern aesthetic ideals — understated, effective, and entirely natural-looking. It does not change who you are -  but it  can help produce healthier, more luminous skin.

Your Next Step

If you’re considering Profhilo® in London, book a consultation at Refind Aesthetics in Islington – we are walking distance from Angel Station so easy to get to. Together, we’ll create a personalised plan that restores your skin’s balance, firmness, and glow.

Book Your Consultation at Refind Aesthetics

Written and reviewed by Dr. Dana Sobhanpanah, GMC-registered medical doctor and founder of Refind Aesthetics, Islington. Trained in Aesthetic Medicine at Harley Academy.

This article is for information purposes only and does not replace medical advice. Profhilo® is a medical device that should only be administered following a face-to-face consultation with a qualified healthcare professional. Results may vary between individuals.